Botanical, Pharmacognosy, and Phytochemical Studies of Sintrong Leaves (Crassocephalum crepidioides) Growing in Tanjung Setia Village, West Coast, Lampung Kajian Botani, Farmakognosi, dan Fitokimia Daun Sintrong (Crassocephalum crepidioides) yang Tumbuh di Desa Tanjung Setia Pesisir Barat Lampung
Main Article Content
Keywords
Crassochepalum crepidioides, sintrong, antibakteri, Asteracea, Thin Layer Chromatography (TLC)
Abstract
Crassochepalum crepidioides plant has antibacterial and anti-wound properties. This study aims to determine the botanical profile, microscopic powder, phytochemical screening, and Thin Layer Chromatography (TLC). This study aims to determine the morphology of leaves, stems, roots, microscopic powder, phytochemical screening, and Thin Layer Chromatography (TLC) of C. crepidioides leaves from Tanjung Setia Village West Coast Lampung, Indonesia. Methods include morphological examination, microscopic powder, phytochemical screening, and TLC. The results of the botanical show oval-shaped leaves, pointed tips, pinnate veins, serrated edges, smooth leaf surface, soft wood stems, and tap roots. Microscopic observation found fragments of stomata. Positive phytochemical screening of alkaloids, flavonoids, saponins, and tannins. TLC test spot with five spots (red) and an average Rf value of 0.21-0.97. Concludes that the thin layer chromatography test is thought to produce flavonoid spots at an Rf value of 0.72-0.77.
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References
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[23] S. Sintupachee, N. Sangphech, and W. Promden, “Assessing the Antioxidant Activity and Anti-inflammatory Potency on Lipopolysaccharide-induced RAW 264.7 Macrophages of Eleven Methanolic Extracts Indigenous Vegetables,” ASEAN Journal of Scientific and Technological Reports, vol. 28, no. 2, p. e255909, Feb. 2025, doi: 10.55164/ajstr.v28i2.255909.
[24] N. P. Widayanti, W. Ayu Saka Laksmita, D. P. R. Vidika Apriyanthi, and I. G. K. Nyoman Arijana, “Lipid Peroxidation Inhibition Activity of Sintrong (Crassocephalum crepidioides) Leaf Extract in Rats Consuming Arak Jembrana,” Makara J Sci, vol. 24, no. 4, pp. 228–232, Dec. 2020, doi: 10.7454/mss.v24i4.1015.
[25] E. Bahar et al., “β-Cell protection and antidiabetic activities of Crassocephalum crepidioides (Asteraceae) Benth. S. Moore extract against alloxan-induced oxidative stress via regulation of apoptosis and reactive oxygen species (ROS),” BMC Complement Altern Med, vol. 17, no. 1, Mar. 2017, doi: 10.1186/s12906-017-1697-0.
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[27] Z. Zhang et al., "Research Progress on the Antibacterial Activity of Natural Flavonoids," April 01, 2025, Multidisciplinary Digital Publishing Institute (MDPI). Doi: 10.3390/antibiotics14040334.
[28] R. Anindita, D. D. Nathalia, M. Perwitasari, I. K. Putri, M. U. Beandrade, and N. R. A. Harahap, “Antibacterial Bioactivity Test of Bilimbi Fruit Ethanol Extract (Averrhoa bilimbi Linn). Against Propionibacterium acnes, Staphylococcus epidermidis and Staphylococcus aureus,” Biology, Medicine, & Natural Product Chemistry, vol. 13, no. 1, pp. 173–182, May 2024, doi: 10.14421/biomedich.2024.131.173-182.
[29] R. Anindita, H. Yolanda, M. Inggraini, S. M. Keluarga, and B. Timur, “Skrining Fitokimia dan Uji Antibakteri Senyawa Ekstrak Etanol Kulit Jeruk Lemon (Citrus limon (L.) Osbeck)Terhadap Staphylococcus aureus,” Jurnal Bioshell: Jurnal Pendidikan Biologi, Biologi, dan Pendidikan IPA, vol. 11, no. 2, p. 2022, 2022, doi: 10.56013/bio.v11i2.1644.
[2] S. Schramm et al., “The Orphan Crop Crassocephalum crepidioides Accumulates the Pyrrolizidine Alkaloid Jacobine in Response to Nitrogen Starvation,” Front Plant Sci, vol. 12, Jul. 2021, doi: 10.3389/fpls.2021.702985.
[3] Fi. A. Lia, “Characterization Of Simplicia And Leaf Extract Of Sintrong (Crassocephalum crepidioides) From East Kalimantan Province As Candidate Drugs For Caries And Its Antibacterial Activity,” Universitas Muhammadiyah Kalimantan Timur, Samarinda, 2022.
[4] P. Ratih Suci, C. Ikhda Nur Hamidah Safitri, and ul Choiroh, “Uji Aktivitas Antibakteri Ekstrak Daun Sintrong (Crassocephalum crepidioides Benth. S. Moore) Pada Salmonella typhi,” Jurnal Farmasi Indonesia AFAMEDIS, vol. 1, no. 2, pp. 1–10, Mar. 2020, doi: https://doi.org/10.61609/afamedis.v1i2.21.
[5] M. S. Asri, S. Hadijah, and K. Dg Mia, “Fraksi Etanol Daun Sintrong (Crassocephalum crepidioides (Benth) S.Moore) Sebagai Bahan Aktif Pembuatan Sabun Cair Antibakteri Terhadap Staphylococcus aureus,” in Prosiding Penelitian dan Pengabdian Karya Cendekia 2024, Mustaqimah, Ahmad Hidayat, Fadhiyah Noor Annisa, Nurul Hidayah, and Rina Saputri, Eds., Banjarbaru, Kalimantan Selatan, Indonesia: WPC Publisher, Sep. 2024, pp. 1–10. doi: https://wpcpublisher.com/jurnal/index.php/prosidingkaryacendekia/article/view/476.
[6] I. T. Lestari, P. R. Suci, E. Fitriany, and N. N. Nafisah, “Aktivitas Antioksidan Dan Skrinning Fitokimia Ekstrak Etanol Daun Sintrong (Crassocephalum crepidioides (Benth) S. Moore),” Jurnal Farmasi Indonesia | AFAMEDIS, vol. IV, no. 1, pp. 1–5, Mar. 2023, doi: https://doi.org/10.61609/afamedis.v4i1.73.
[7] N. M. Can, D. T. P. Thao, and G. Gil, “Wound Healing Activity of Crassocephalum crepidioides (Benth.) S. Moore. Leaf Hydroethanolic Extract,” Oxid Med Cell Longev, vol. 2020, pp. 1–10, 2020, doi: 10.1155/2020/2483187.
[8] A. Sakpere, O. Adedeji, and A. Folashade, "Flowering, post-pollination development and propagation of Ebola (Crassocephalum crepidioides (benth.) S. Moore) in Ile-Ife, Nigeria,” Journal of Science and Technology (Ghana), vol. 33, no. 2, p. 37, Dec. 2013, doi: 10.4314/just.v33i2.4.
[9] K. Kartini, R. E. Putri, and R. Budiono, “Quantification of sinensetin in Orthosiphon stamineus from various phytogeographical zones in Indonesia,” J Appl Pharm Sci, vol. 13, no. 3, pp. 183–191, 2023, doi: 10.7324/JAPS.2023.80035.
[10] M. Silalahi, “Crassocephalum crepidioides (Bioactivity and Utilization),” in ICES 2021, November 17-18, Jakarta, Indonesia, European Alliance for Innovation n.o., Jul. 2022. doi: 10.4108/eai.17-11-2021.2318673.
[11] V. R. Puspa, Zumaidar, Nurdin, and Fitmawati, “Species diversity of Asteraceae in Gayo Highlands, Bener Meriah District, Aceh Province, Indonesia,” Biodiversitas, vol. 25, no. 6, pp. 2828–2837, 2024, doi: 10.13057/biodiv/d250639.
[12] D. Krisdiyanti and J. Batoro, “Types of Wild Plant of Asteraceae Family Potentially as Herbicide in Brawijaya University,” Basic Sciences of Medicine, vol. 8, no. 1, pp. 1–11, Aug. 2019, doi: 10.5923/j.medicine.20190801.01.
[13] A. Kurniawati, U. M. R. Utama, E. S. Aziz, and D. N. Faridah, “Morphophysiology of indigenous vegetable Sintrong ( Crassocephalum crepidiodes) from several areas in West Java,” in IOP Conference Series: Earth and Environmental Science, Institute of Physics, 2023, pp. 1–10. doi: 10.1088/1755-1315/1220/1/012013.
[14] B. Nordenstam, "Ignurbia, a new genus of the Asteraceae-Senecioneae from Hispaniola," Willdenowia, vol. 36, no. 1, pp. 463–468, Feb. 2006, doi: 10.3372/wi.36.36144.
[15] Dorly, “Anatomi Daun Lima Jenis Anggota Suku Asteraceae Di Situ Gunung,” 2024. doi: https://repository.ipb.ac.id/jspui/bitstream/123456789/160380/1/ARTIKEL_DORLY_ANATOMI%20DAUN%20ASTERACEAE.pdf.
[16] U. M. R. Utama, A. Kurniawati, and D. N. Faridah, “Physiological Responses of Indigenous Vegetable of Sintrong (Crassocephalum crepidioides) due to Exposure to High Temperature,” Caraka Tani: Journal of Sustainable Agriculture, vol. 38, no. 1, pp. 163–175, Apr. 2023, doi: 10.20961/carakatani.v38i1.67163.
[17] Z. S. A. Rashid, C. N. A. C. Amri, and R. Shahari, “The Taxonomic Study Of Trichome Morphology In Selected Asteraceae Species Of Pahang, Malaysia,” Malaysian Applied Biology, vol. 51, no. 4, pp. 1–4, 2022, doi: 10.55230/mabjournal.v51i4.01.
[18] N. Malik, Sahidin, Muhidin, and A. Fristiohady, “Growth Response and Antibacterial Activity Test of Sintrong Plant (Crassocephalum crepidioides (Benth.) S. Moore) on different Growth Media and Shade,” Journal of Global Innovations in Agricultural Sciences, vol. 12, no. 2, pp. 277–283, 2024, doi: 10.22194/JGIAS/24.1227.
[19] C. L. Ringmichon, “Pharmacognostic standardization of Crassocephalum crepidioides (Benth.) S. Moore: An antipyretic leaf drug,” in American Journal of Ethnomedicine, Scitechnol Biosoft Pvt. Ltd., 2019. doi: 10.21767/2348-9502-c1-008.
[20] Y. A. Devi, P. Gnanasekaran, and H. J. Devi, “Antibacterial, Antioxidant and Cytotoxicity Assessment of Crassocephalum crepidioides Leaf Extract,” J Pure Appl Microbiol, vol. 18, no. 4, pp. 2528–2538, Dec. 2024, doi: 10.22207/JPAM.18.4.24.
[21] A. B. Falowo, O. D. Oloruntola, and O. F. Akinmoladun, “Assessment of Nutritional Composition and Antioxidant Properties of Dysphania ambrosioides (L.) Mosyakin & Clemants and Crassocephalum crepidioides Leaf Meal as Potential Feed Additives,” Turkish Journal of Agriculture - Food Science and Technology, vol. 11, no. 2, pp. 274–279, Feb. 2023, doi: 10.24925/turf.v11i2.274-279.5603.
[22] O. M. Bello, A. S. Umar, and M. H. Sada, “Profiling of Secondary Metabolites from Crassocephalum crepidioides (Wild Leafy Vegetable): Validation of Ethnomedicinal Claim by in-vitro and in-silico Studies,” Journal of Applied Sciences and Environmental Management, vol. 27, no. 7, pp. 1337–1344, Jul. 2023, doi: 10.4314/jasem.v27i7.2.
[23] S. Sintupachee, N. Sangphech, and W. Promden, “Assessing the Antioxidant Activity and Anti-inflammatory Potency on Lipopolysaccharide-induced RAW 264.7 Macrophages of Eleven Methanolic Extracts Indigenous Vegetables,” ASEAN Journal of Scientific and Technological Reports, vol. 28, no. 2, p. e255909, Feb. 2025, doi: 10.55164/ajstr.v28i2.255909.
[24] N. P. Widayanti, W. Ayu Saka Laksmita, D. P. R. Vidika Apriyanthi, and I. G. K. Nyoman Arijana, “Lipid Peroxidation Inhibition Activity of Sintrong (Crassocephalum crepidioides) Leaf Extract in Rats Consuming Arak Jembrana,” Makara J Sci, vol. 24, no. 4, pp. 228–232, Dec. 2020, doi: 10.7454/mss.v24i4.1015.
[25] E. Bahar et al., “β-Cell protection and antidiabetic activities of Crassocephalum crepidioides (Asteraceae) Benth. S. Moore extract against alloxan-induced oxidative stress via regulation of apoptosis and reactive oxygen species (ROS),” BMC Complement Altern Med, vol. 17, no. 1, Mar. 2017, doi: 10.1186/s12906-017-1697-0.
[26] N. F. Shamsudin et al., "Flavonoids as Antidiabetic and Anti-Inflammatory Agents: A Review on Structural Activity Relationship-Based Studies and Meta-Analysis," October 01, 2022, MDPI. doi: 10.3390/ijms232012605.
[27] Z. Zhang et al., "Research Progress on the Antibacterial Activity of Natural Flavonoids," April 01, 2025, Multidisciplinary Digital Publishing Institute (MDPI). Doi: 10.3390/antibiotics14040334.
[28] R. Anindita, D. D. Nathalia, M. Perwitasari, I. K. Putri, M. U. Beandrade, and N. R. A. Harahap, “Antibacterial Bioactivity Test of Bilimbi Fruit Ethanol Extract (Averrhoa bilimbi Linn). Against Propionibacterium acnes, Staphylococcus epidermidis and Staphylococcus aureus,” Biology, Medicine, & Natural Product Chemistry, vol. 13, no. 1, pp. 173–182, May 2024, doi: 10.14421/biomedich.2024.131.173-182.
[29] R. Anindita, H. Yolanda, M. Inggraini, S. M. Keluarga, and B. Timur, “Skrining Fitokimia dan Uji Antibakteri Senyawa Ekstrak Etanol Kulit Jeruk Lemon (Citrus limon (L.) Osbeck)Terhadap Staphylococcus aureus,” Jurnal Bioshell: Jurnal Pendidikan Biologi, Biologi, dan Pendidikan IPA, vol. 11, no. 2, p. 2022, 2022, doi: 10.56013/bio.v11i2.1644.
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Jun 18, 2025
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Anindita, R., Pratama, G. C., Putri, I. K., Beandrade, M. U., & Futihat, C. E. (2025). Botanical, Pharmacognosy, and Phytochemical Studies of Sintrong Leaves (Crassocephalum crepidioides) Growing in Tanjung Setia Village, West Coast, Lampung: Kajian Botani, Farmakognosi, dan Fitokimia Daun Sintrong (Crassocephalum crepidioides) yang Tumbuh di Desa Tanjung Setia Pesisir Barat Lampung. Jurnal Ilmiah Biologi Eksperimen Dan Keanekaragaman Hayati (J-BEKH), 12(1), 81–94. https://doi.org/10.23960/jbekh.v12i1.423
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